| slmx | Simulink Model Requirements Links Data |
| sln | SYBYL Line Notation Data |
| slnk | SAPLink Slinkee Data |
| slo | RenderMan Shader Data |
| slo8 | TERC V.I.P. Data |
| slo9 | TERC V.I.P. Data |
| slob | Slob Dictionary Data |
| slog | Autodesk Revit Worksharing Log |
| slow | Notepad++ SLOW Data |
| slp | Sage Timeslips Data |
| slr | SWAT Solar Radiation Data |
| slreqx | Simulink Requirements Data |
| slst | On Schedule Data |
| slt | DB/TextWorks Slot Log File |
| slt | ZX Spectrum Emulator SLT Snapshot |
| sltx | Simulink Model Template |
| slu | Business Integrator Upgrade License Data |
| slw | Settler LITE Data File |
| slx | Simulink Model Data |
| slxc | Simulink Model Cache Data |
| slxp | MATLAB Protected Model |
| sm2 | SAS Multi-dimensional Database |
| sm3 | DataCAD Symbol File |
| sm4 | XPMPro 2.0 Data |
| sm7 | SAS Multi-dimensional Database |
| smap | WHAMM Segment Map File |
| smb | Autodesk Mapguide Symbol Library |
| smc | SNES ROM Image SMC |
| smc | Yaskawa YTerm Data |
| smd | Sega Genesis ROM |
| smdh | Nintendo 3DS Homebrew Application Data |
| smdx | SunSpec Model Definition XML Data |
| smf | Lowrance StructureMap File |
| smf | QSlim 3D Model |
| smf | SmartCAM Manufacture File |
