| sbk | SWiSH Max Backup Data |
| sbkt | Scrapbook Data |
| sbl | Microsoft Accounting SQL Server Log |
| sbn | ScadaWorks Node Data |
| sbo | SAP Business One SDK Add-on Related Data |
| sbox | sBOX Meta-file |
| sbp | OpenSBP CNC Program |
| sbq | Superbase Quick Report File |
| sbr | ScadaWorks ScadaBuilder Data |
| sbs | SPSS Script |
| sbs | SpyBot Search and Destroy Include |
| sbs | SWAT HRU Output Data |
| sbstore | Mozilla Firefox Safebrowsing Database |
| sbt | Superbase Data Notes |
| sbv | Superbase Form Definition Data |
| sbw | US Treasury Savings Bonds Wizard Data |
| sc | IBM EMMS Secure Container |
| sc0 | Structure Survey Editor Profile |
| sc2 | SAS Catalog |
| sc7 | SAS Catalog |
| scad | OpenSCAD Script |
| sccef | StreamCryptor Chunked Encrypted Dat |
| sccm | System Center Configuration Manager file |
| sccs | SCCS Data |
| scd | Intuit TurboTax Tax Line Items |
| scdata | RSSIM Scene Reflectance Data |
| sce | YASARA Scene |
| scel | Sogou Pinyin Cell Dictionary Data |
| scenario | Yarn Data |
| scene | VCollab Pro Scene Data |
| scexcludb | Spring Cleaning Exclusions Data |
| scgc | myPM SCG Classic Data |
| scgp | myPM SCG Pro Data |
| scgs | myPM SCG Starter Data |
| sch | Microsoft SQL Server Data Replication Schema |
