| enigma64 | Enigma Protector x64 Data |
| entitlements | App Sandboxing Entitlements |
| ephtml | Enhanced Perl-parsed HTML |
| epl | TallyMan EPL File |
| erb | Erubis Script |
| erb | Ruby ERB Script |
| erbsql | Ruby ERB SQL Script |
| erc | Ercato Engine Code |
| erd | Active Media Eclipse Data |
| erl | Erlang Source Code |
| erlang | Erlang Source Code |
| ers | Altium Designer Assembler Error Messages File |
| erubis | Erubis Script |
| es | ECMAScript Source Code |
| es | Sage CRM Script |
| es4 | ECMAScript 4 Source Code |
| es5 | ECMAScript 5 Source Code |
| es6 | ECMAScript 6 Source Code |
| esav | ANSYS Element Saved Data |
| escn | Godot Engine Exported Scene Data |
| esk | ESock Module Information |
| esl | Microsoft Visual FoxPro Support Library |
| essl | OpenGL ES Shader Language Data |
| esv | Uniface Entity Service Data |
| eto | Visual Studio Enterprise Template Object |
| eu | Euphoria Include File |
| ev3b | Lego Mindstorms EV3 Block File |
| ev3m | Lego Mindstorms EV3 for iPad Program |
| ew | Euphoria Include File |
| ewd | IAR System Debugger Data |
| ewo | SIMATIC WinCC External Widget Object |
| ewu | Embedded Wizard Unit |
| eww | IAR System Workspace Data |
| ex | Euphoria Source Code |
| ex2 | ParaView EX2 Mesh Data |