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TPR file extension

The table below provides useful information about the .tpr file extension. It answers questions such as:

  • What is the .tpr file?
  • What program do I need to open a .tpr file?
  • How can the .tpr file be opened, edited or printed?
  • How can I convert .tpr files to another format?

We hope you find this page helpful and a valuable resource!

1 extension(s) and 0 alias(es) found in database

✅ GROMACS Portable Binary Input File

TPR file is a GROMACS Portable Binary Input File. GROMACS (GROningen MAchine for Chemical Simulations) is a molecular dynamics simulation package originally developed in the University of Groningen. The tpr file extension stands for portable binary run input file. This file contains the starting structure of your simulation, the molecular topology and all the simulation parameters
Category: Data files
Application: GROMACS
Mime-type: application/octet-stream
Magic number: -
Magic string: -
Sample: -
TPR aliases:
TPR related links:
TPR related extensions:
GROMACS System Topology

GROMACS Include Topology

GROMACS Residue Topology

Grace Document


GROMACS Binary Input File


GROMACS Trajectory File

GROMACS Binary Energy File

GROMACS Portable Energy Data

Other types of files may also use the .tpr file extension.

🚫 The .tpr file extension is often given incorrectly!

According to the searches on our site, these misspellings were the most common in the past year:

fpr, gpr, hpr, pr, ptr, rpr, tlr, tor, tp, tpd, tpe, tpf, tpg, tpt, tr

Is it possible that the filename extension is misspelled?

We found the following similar file extensions in our database:

BitTorrent Meta File
Sun Icon/Cursor
Squeak Project
Fun Photor Template
Transit NXT Translation Project
MotionTracking Track Search Parameters Data
Tableau Offline License Registration Data
HAHTsite Project
CIRS Transaction Data
Commodore 64 FLI Profi Image

🔴 Can't open a .tpr file?

When you double-click a file to open it, Windows examines the filename extension. If Windows recognizes the filename extension, it opens the file in the program that is associated with that filename extension. When Windows does not recognize a filename extension, you receive the following message:

Windows cannot open this file:


To open this file, Windows needs to know what program you want to use to open it...

If you don't know how to set the .tpr file association, check the FAQ.

🔴 Can I change the extension of files?

Changing the filename extension of a file is not a good idea. When you change a file's extension, you change the way programs on your computer read the file. The problem is, changing the file extension does not change the file format.

If you have helpful information about the .tpr file extension, write to us!

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