A daily updated filename extension database!

SMI file extension

The table below provides useful information about the .smi file extension. It answers questions such as:

  • What is the .smi file?
  • What program do I need to open a .smi file?
  • How can the .smi file be opened, edited or printed?
  • How can I convert .smi files to another format?

We hope you find this page helpful and a valuable resource!

1 extension(s) and 2 alias(es) found in database

✅ Synchronized Multimedia Integration Language

SMI file a Synchronized Multimedia Integration Language document. SMIL is a W3C Recommended XML markup language for describing multimedia presentations.
Category: Multimedia files
Application: Windows Media Player
Mime-type: application/x-smil
Magic number: -
Magic string: -
Sample: -
SMI aliases:
SMI related links:
SMI related extensions:
Extensible Markup Language File

M3U Playlist File

M4U Playlist File

RealPix Clip

XML Shareable Playlist File

Sandisk Sansa Playlist

✅ SAMI Captioning File

SAMI file is a SAMI Captioning File. SAMI (Synchronized Accessible Media Interchange) is an interchange format for the support of Closed Captions, and Audio Descriptions.
Category: Multimedia files
Application: Subtitle Workshop
Mime-type: application/octet-stream
Magic number: -
Magic string: -
Sample: -
SAMI aliases:
SAMI related links:
SAMI related extensions:

✅ SMILES Chemical Document

SMILES file is a SMILES Chemical Document. The Simplified Molecular Input Line Entry Specification (SMILES) is a line notation for molecules. SMILES strings include connectivity but do not include 2D or 3D coordinates.
Category: Data files
Application: Daylight PCModels
Mime-type: chemical/x-daylight-smiles
Magic number: -
Magic string: -
Sample: -
SMILES aliases:
SMILES related links:
SMILES related extensions:

Other types of files may also use the .smi file extension.

🚫 The .smi file extension is often given incorrectly!

According to the searches on our site, these misspellings were the most common in the past year:

cmi, emi, mi, msi, shi, si, sim, ski, sli, sm, smk, sml, smo, smu, sni

Is it possible that the filename extension is misspelled?

We found the following similar file extensions in our database:

AutoDesk Softimage Document
CoCreate Document
Pocket Tanks Emitter File
WeintekHMI EasyBuilder 8000 EMI File
SMIL Document
Simile Model
Aurora Image
Steam Game Backup Metadata
CARE-S InfoWorks Simulation Parameters Data
Microsoft Windows Installer Package

🔴 Can't open a .smi file?

When you double-click a file to open it, Windows examines the filename extension. If Windows recognizes the filename extension, it opens the file in the program that is associated with that filename extension. When Windows does not recognize a filename extension, you receive the following message:

Windows cannot open this file:


To open this file, Windows needs to know what program you want to use to open it...

If you don't know how to set the .smi file association, check the FAQ.

🔴 Can I change the extension of files?

Changing the filename extension of a file is not a good idea. When you change a file's extension, you change the way programs on your computer read the file. The problem is, changing the file extension does not change the file format.

If you have helpful information about the .smi file extension, write to us!

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