| edrwx | Microsoft XPS Drawing Document |
| edw | SolidWorks eDrawings Document |
| edx | Edraw Max Document |
| edxz | Edraw Max Compressed Document |
| eef | Embird Editor File |
| ef3 | eFax Document |
| efax | eFax Document |
| efm | Electronic Fiction Manuscript |
| efr | Elixir DesignPro Tools New Form |
| efw2 | Electronically Filled W-2 Form |
| efw2c | Electronically Filled W-2c Form |
| efx | eFax Document |
| egc | EximiousSoft GIF Creator Document |
| egx | EasyGrapher Document |
| eim | Electric Image Model |
| ejf | Zebra EPL2 Label |
| elfo | ElsterFormular Form |
| elx | Elixir DesignPro Tools Form |
| email | Microsoft Outlook Express E-Mail |
| emaze | Emaze Presentation |
| emcmf | EMC Documentum Message |
| emcx | Mastercam X Educational Document |
| eml | Microsoft Outlook Express E-Mail |
| emr | Emrite Document |
| eng | Readme Text |
| enml | Evernote for Android Note |
| ent | SGML/XML External Entity |
| env | Broderbund PrintMaster Envelope |
| enx | EverNote Document |
| eof | Embird Vector Embroidery Format File |
| eop | Everyone Piano Music Score File |
| eopm | EOP Music Master Composed Music |
| eot | ExamView Online Test Data |
| epdf | Encapsulated Portable Document Format |
| epix | Piranesi EPix Image |