| ds4 | DeSmuME Saved State |
| ds5 | WinDS PRO Data |
| ds6 | WinDS PRO Data |
| ds7 | WinDS PRO Data |
| ds8 | WinDS PRO Data |
| ds9 | WinDS PRO Data |
| dsb | Barudan Embroidery Data |
| dsc | Bio-Rad DNA Scan Code |
| dsc | Nikon Disk Identification |
| dsc | Softimage 3D Scene |
| dsce | Diagnosis Scenario Data |
| dsd | CARE-S InfoWorks Nodes Data |
| dsd | DAZ Studio Deltas |
| dsd | Diet Studio Data |
| dsdb | CFX Simulation Database |
| dsdf | DigitalDreams Secure Data Transfer File |
| dsdic | HelpSmith Dictionary Data |
| dsdict | DS Dictionary Data |
| dseg | Stuffit DropSegment Data |
| dsf | DataCAD 15 Symbol File |
| dsf | DSON Support File |
| dsf | Racelogic PerformanceBox Split Data |
| dsft | Microsoft App-V Differential SFT File |
| dsh | Dashboard Wallpaper |
| dsidx | Dash DocSet Index Data |
| dsim | Digital Simulator Data |
| dsk | RAD Studio Saved Desktop |
| dskin | DockX Skin Data |
| dsm | AQUA Generic Distance Restraints Summary Data |
| dsn | ODBC Data Source Name |
| dsn | SPECCTRA Design File |
| dso | DAZ Studio Object |
| dspackage | Desktop Sidebar Package |
| dsq | Torque 3D Animation Data |
| dss | WRAP Simulation Results Output Data |