| drb | Dr. Beam Pro Data |
| drc | OMA DRM Rights Object WebXML |
| dre | DReport Exported Report |
| drg | Carlson Survey Drawings Data |
| dri | Excellion Drill File |
| dri | Microsoft SQL Server Data Replication Index |
| drill | DROPS Simulator Operation Data |
| drk | Race Studio 2 Downloaded Files |
| drl | Excellon Drill File |
| drl | Altium Binary Drill File |
| droid | DROID Profile |
| drq | SDLX De-registration Request Data |
| drr | Altium Drill Report File |
| drs | SPSS Raw Response Data |
| drt | PSpice Custom Derating |
| dru | EAGLE Design Rules File |
| drwprp | SolidWorks Drawing Properties Template |
| drx | DaVinci Resolve eXchange File |
| dry | XAIRON Organizer Diary Data |
| ds | Pasco DataStudio Data |
| ds0 | DeSmuME Saved State |
| ds1 | DeSmuME Saved State |
| ds2 | DeSmuME Saved State |
| ds3 | DeSmuME Saved State |
| ds4 | DeSmuME Saved State |
| dsb | Barudan Embroidery Data |
| dsc | Nikon Disk Identification |
| dsc | Softimage 3D Scene |
| dsc | Bio-Rad DNA Scan Code |
| dsd | DAZ Studio Deltas |
| dsd | CARE-S InfoWorks Nodes Data |
| dsd | Diet Studio Data |
| dsdb | CFX Simulation Database |
| dsdic | HelpSmith Dictionary Data |
| dseg | Stuffit DropSegment Data |