| s5r | VecTor5 Structure Data |
| s6p | EEsof Touchstone File |
| s7d | Sony Ericsson S700i Phone Default Language |
| s7m | SAS Data Mining Database |
| s7s | Sony Ericsson S700i Phone Firmware |
| s8 | SIMUL8 Simulation |
| s85 | Sabre Airline Solutions Chart |
| s8theme | Start8 Theme Data |
| s99 | MicroStation Modification Site Resource File |
| sa | ParFlow Simple ASCII Data |
| sa2 | SAS Access Descriptor |
| sa3 | WinDS PRO Data |
| sa4 | STABCAL Data |
| sa7 | SAS Access Descriptor |
| sab | Standard ACIS Binary |
| sab2 | NVision 3D Scanner Data |
| sac | IRIS SAC File |
| sac | Scream Recorded SAC Data |
| sad | Windows Server Security Association Database |
| sae | Sage Accountant Link |
| safetext | SafeText Data |
| saff | SuperStream Alternative File Format Data |
| sah | SETI@home Data |
| sai | Burrows-Wheeler Alignment Tool SAI Data |
| saj | Sage 50 Folder Data |
| sal | WRAP Salinity Simulation Results Data |
| sam | PaleoMag ASCII Sample Data |
| sam07 | SAM 2007 Package |
| samp | Apache Drill Sample Data |
| sapssd | SAP GUI Data |
| sas7bacs | SAS Access Descriptor |
| sas7baud | SAS Audit Data |
| sas7bbak | SAS Backup |
| sas7bcat | SAS Catalog |
| sas7bdat | SAS Data Set |