| scdata | RSSIM Scene Reflectance Data |
| sce | YASARA Scene |
| scenario | Yarn Data |
| scene | VCollab Pro Scene Data |
| sch | Microsoft SQL Server Data Replication Schema |
| sch | TINA Schematic Data |
| schdoc | Altium Designer Schematic File |
| schemas | GNOME GConf Schema Definition |
| schk | SortSite Site Data |
| schlib | Altium Designer Schematic Library |
| scml | Spriter Data |
| scmt | GXS Application Integrator XML Constraint |
| scn | AutoDesk Softimage Scene |
| sco | Microsoft IIS Schema Backup |
| scp | SCP-ECG Data |
| scpb | Survivorship Care Plan Builder Data |
| scprt | Surfcam 3D Format Data |
| scs | Siemens Mobil Phone Color Skin |
| scs | StuffIt Saved File List |
| scssc | Sass Compiled Data |
| sctid | RSA SecurID Software Certficate Import Data |
| scy | ReaGeniX License Data |
| sd | STK Satellite Database Main File |
| sd2 | SAS Data Set |
| sd3 | Hy-Tek Meet Manager SDIF Data |
| sd4 | Smart Diary Suite 4 Database |
| sd7 | Daktronics Venus 7000 Schedule Data |
| sd7 | SAS Data Set |
| sdac | CoCreate OneSpace Assembly Container Data |
| sdbs | BLAST+ Personal Database |
| sdbx | Autodesk AutoCAD Civil 3D Survey Database |
| sdbz | Symantec EP Support Tool Information File |
| sdct | Pocket Diary Spelling Dictionary |
| sddb | Medi-Span Standard Drug Database |
| sdexp | PTC Creo Elements/Direct Model Export Data |
